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With the year winding down, we've witnessed numerous transactions in the space at absolutely gobsmacking premiums. Here is a brief overview of the biggest deals over the past two months. Best of all, this trend should endure well into the new year. Several top pharmas, after all, are currently dealing with major patent expires, novel competition entering the marketplace, as well as pressure from lawmakers to rethink their drug pricing policies.

Which biotechs could be the next to be bought out? Here's what investors need to know about these top buyout candidates right now. After a positive advisory committee vote for Vascepa's proposed label expansion as an add-on to statin therapy in patients with stubbornly high triglyceride levels last month, Amarin arguably stands out as a perfect bolt-on acquisition for several big pharmas.

The Food and Drug Administration is expected to issue a final decision on the drug's label expansion application before the end of the year. What's more, Amarin appears to be built for a takeover.

The company has no other product candidates in the pipeline at the moment, it doesn't have the financial capacity to both build a pipeline from scratch and promote Vascepa properly, and there's no doubt that Vascepa would be significantly more valuable in the hands of a big pharma. The bottom line is that management is likely to at least entertain potential suitors once Vascepa's label is a known quantity.

That said, price could be a sticking point.

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Management clearly believes that Vascepa has Lipitor-like sales potential, but suitors may not be willing to pay that kind of price tag. In that case, Amarin's best bet might be to strike a co-promotional deal with a big pharma or blue chip biotech. Such a move would maximize Vascepa's commercial potential, while simultaneously creating the leverage needed to demand top dollar in a buyout later down the line.

On Dec. However, Wall Street clearly didn't have high expectations for voclosporin's lupus nephritis trial leading into this top-line data readout. That's the kind of commercial opportunity that tends to attract big pharma suitors. What's next?

Achillion Pharmaceuticals' stock rockets after Alexion Pharmaceuticals $930 million buyout deal

Aurinia plans to file for the drug's approval with the FDA sometime in the first half of next year. Before this regulatory filing ever sees the light of day, however, Aurinia could fetch a sizable takeover offer. The long and short of it is that the biotech now sports a well-differentiated product candidate with strong late-stage data.

So, if management chooses to go the buyout route, there should be ample interest from big pharma. Dec 11, at AM. Author Bio George Budwell has been writing about healthcare and biotechnology companies at the Motley Fool since His primary interests are novel small molecule drugs, next generation vaccines, and cell therapies.

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Skip to content. Home About Me Contact Me. December 13, fsdadmin Leave a comment. December 12, fsdadmin Leave a comment.

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December 10, fsdadmin Leave a comment. December 9, fsdadmin Leave a comment. December 6, fsdadmin Leave a comment. December 5, fsdadmin Leave a comment. December 4, fsdadmin Leave a comment. December 3, fsdadmin Leave a comment. December 2, fsdadmin Leave a comment.Titan is advancing the treatment of select chronic diseases by developing therapeutics based on its proprietary long-term, continuous drug delivery platform, ProNeura.

Kate Beebe-DeVarney explain the advantages of the ProNeura long-term continuous drug delivery platform. Watch the Mechanism of Action video for the ProNeura technology platform and learn how continuous drug release maintains stable blood levels of medication to help treat chronic diseases. Market in progress. Phase 1 in progress. Phase 1 not started. Preclinical not started.

About Titan Pharmaceuticals Titan is advancing the treatment of select chronic diseases by developing therapeutics based on its proprietary long-term, continuous drug delivery platform, ProNeura. More About Titan Pharmaceuticals.

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pharma buyout

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2 Pharma Buyout Targets That May Surprise You

View SEC Filings. Market completed. Phase 1 completed. Preclinical in progress.RTTNews - saw more than 25 acquisition deals being executed in the biotech sector, of which 14 were billion-dollar deals. Let's take a look at some of the biotech companies that have been in the acquisition crosshairs for quite some time.

Like the Medicines Co. Vascepa secured its first FDA approval in for treating patients with very high triglyceride levels and as recently as yesterday Dec. Alexion Pharma is no stranger to takeover rumors.

This developer of rare disease drug Soliris has been in acquisition crosshairs since - with Roche, Pfizer, Novartis and Amgen been reported as potential buyers. In Augustrumor mills were abuzz with the news that Alexion Pharma may be up for sale after Intereconomia.

But that deadline has long passed. Meanwhile, earlier this month, U. However, the Company has turned down Elliott's recommendation. BioMarin is almost every analyst's favorite takeover candidate. This biotechnology company, which operates in hemophilia and ultra-orphan disease drug space, has seven approved treatments, a strong pipeline, and steadily growing revenue.

Inthere were reports that Roche was eyeing BioMarin for a possible acquisition. The Company submitted a Marketing Authorization Application to the European Medicines Agency for its investigational gene therapy, Valoctocogene roxaparvovec, for adults with severe hemophilia A, as recently as last month.

This submission marks the first marketing application submission for a gene therapy product for any type of hemophilia. The review of the application by the EMA is expected to commence in January under accelerated assessment.

23andMe Buyout to Big Pharmaceuticals

Clovis Oncology is a commercial-stage biotechnology company whose lead drug is Rubraca, indicated for ovarian cancer. Takeover rumors initially swirled around Clovis Oncology in when Rubraca, was in clinical trial stage. Now, it is three years since the PARP inhibitor has been approved.

Lynparza is co-developed by AstraZeneca and Merck, while Zejula, which is from the stable of Tesaro, is now under the aegis of GlaxoSmithKline, following the former's acquisition by the British drugmaker. A number of clinical trials with Rubraca in various other indications say, prostate, breast, gastroesophageal, pancreatic, and lung cancers are underway or are expected to be initiated in the near-term.

Incyte has an attractive pharmaceutical portfolio comprising of Jakafi, a blockbuster drug for rare blood cancer indications, and 3 other marketed drugs, and a well-stocked pipeline.

But following Gilead's decision to acquire Kite Pharma in August of that year, the rumors died down. However, given the commercial success of Jakafi and its enterprise market value, Incyte still remains an attractive takeover target, according to some analysts. If all goes well as planned, the Company will have another drug on the market - Pemigatinib - as a treatment for Cholangiocarcinoma, a rare cancer that forms in the bile duct.

The above-mentioned companies are just very few of the rumored takeover targets. It remains to be seen if the takeover rumors are just wishful thinking or will turn into reality. Oncology and gene therapy were the subjects of acquisitions this year. A report from industry analyst IQVIA suggests that "significant deal activity, both in terms of volume and value, will continue to be seen in oncology, with next-generation biological therapies such as neoantigen-directed approaches likely to attract considerable big pharma interest".

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. Markets ALXN. Latest Markets Videos. See more videos. Your Watchlist is empty.Driven to transform the lives of patients and families affected by diseases of the complement alternative pathway. At Achillion, we are driven to transform the lives of patients and families affected by diseases of the complement system, an integral part of the innate immune system.

pharma buyout

Scientific and clinical evidence has implicated the complement system, and specifically the complement alternative pathway AP in numerous devastating diseases and conditions. Our principal focus at Achillion is to advance our clinical-stage portfolio of orally administered factor D inhibitors into late-stage development and potential commercialization for patients with devastating disorders of the complement system.

We are actively assessing two clinical stage, oral factor D inhibitors, danicopan ACH and, second-generation, ACH in Phase 2 and 1 studies, respectively.

Achillion Pharmaceuticals. Learn More.

Array BioPharma's stock rockets after $11.4 billion buyout deal with Pfizer

Achillion Pharmaceuticals At Achillion, we are driven to transform the lives of patients and families affected by diseases of the complement system, an integral part of the innate immune system.

Complement Mediated Diseases. Our Science. Patients and Clinicians. Achillion has been acquired by Alexion Pharmaceuticals, Inc. For more information, click here. Achillion Pharmaceuticals, Inc.Mergers and acquisitions can be extremely profitable for pharmaceutical investors.

Here's why. Biogen's name hasn't floated to the top of many buyout rumor mills lately, and perhaps for good reason. Biogen may prove to be an attractive target for two reasons. Put simply, that's a great price for a bolt-on acquisition that should be accretive to earnings right away, and there simply aren't a whole lot of similar valuation scenarios floating around the industry these days.

Second, Biogen has two particular assets under its roof that might trigger a buyout. If approved, this drug could turn out to be the best-selling medicine of all time by a wide margin. The downside is that aducanumab belongs to a class of drugs that have repeatedly failed to show any signs of efficacy in pivotal-stage trials -- meaning that this drug is without a doubt a long shot.

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Still, big pharma has plowed literally billions into similar drugs time and again -- despite any lack of proof that they work. So it shouldn't come as a shock if aducanumab turns out to be a key reason Biogen gets taken out.

Spinraza is an especially attractive asset for a potential acquirer because it's an orphan medication, so it comes with an extended period of exclusivity, and it will probably turn out to be largely immune to any potential drug pricing reforms. The overarching reason is obvious: Opdivo. Despite the tenacity of these rumors, however, Bristol has yet to receive a formal offer -- at least one that's been made public.

Presumably, potential suitors are concerned about Opdivo's ability to break into earlier lines of therapy for its most valuable indication -- non-small cell lung cancer NSCLC -- and to stave off competitors in later-line settings as well. Opdivo, after all, flamed out in a clinical trial as a monotherapy for NSCLC and its ongoing combination study with Bristol's Yervoy is showing some worrisome signs as well.

The bigger picture, though, is that Bristol is without question transforming into an immuno-oncology giant, regardless of this hiccup in NSCLC. That's an enormously appealing feature to a company that has largely failed to establish its own oncology franchise like Gilead. As an added bonus, Bristol also sports two additional legit franchise-level drugs. But Pfizer is a definite contender to make a play for Bristol based on their shared interests in immuno-oncology, cardiovascular care, and anti-inflammatory diseases.

Stay tuned. Although you should arguably never buy a stock simply because of its potential as a buyout candidate, there's no denying that another wave of consolidation is eventually going to sweep across the biopharmaceutical landscape soon. So it's probably a good idea to at least have this secondary value driver in the back of your mind when buying biotech and biopharma stocks right now. In regards to Biogen and Bristol, these two companies both offer modest near-term growth prospects, fairly clean balance sheets, and some intriguing clinical assets.

As such, a buyout thesis certainly isn't necessary in order to consider adding these top pharma names to your portfolio. Nevertheless, the current environment does lend credence to a takeover scenario in each case -- making it worthwhile to ponder as a possible near-term catalyst. Jun 27, at AM. Author Bio George Budwell has been writing about healthcare and biotechnology companies at the Motley Fool since His primary interests are novel small molecule drugs, next generation vaccines, and cell therapies.

Image source: Getty Images. Stock Advisor launched in February of Join Stock Advisor. Related Articles.Yesterday, the conglomerate received a green signal from the U.

With this, it completed all requirements for getting antitrust clearances for the buyout. Notably, Danaher announced the buyout deal in February The BioPharma business comprises single-use technologies, process chromatography hardware and related consumables, development instrumentation and related consumables, cell culture media and service.

Inside the Headlines Danaher also noted that the buyout received clearances from the European Commission as well as antitrust authorities of Korea, Brazil, Russia, China, Israel and Japan. The transaction is anticipated to close on Mar 31, after the fulfillment of conditions mentioned in the purchase agreement.

Also, it will assume certain pension liabilities of General Electric.

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Post the completion of the buyout, Danaher will integrate the BioPharma business with its Life Sciences segment. Earnings accretion of 60 cents per share is anticipated in disclosed in January from the buyout. Previously, Danaher had expected cents per share earnings accretion in the first year of the deal completion.

Danaher acquired Labcyte Corporation in January The company is poised to benefit from product innovation, Danaher Business System, shareholder-friendly policies and inorganic initiatives. However, forex woes, high costs and huge debts remain concerning. In the past 30 days, the Zacks Consensus Estimate for its earnings has been lowered by 2. Danaher Corporation Price and Consensus.

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Both stocks currently carry a Zacks Rank 2 Buy. In the past 30 days, earnings estimates for Griffon have improved for the current year, while have been unchanged for Hitachi.

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